218776
Caspase-9 Inhibitor II, Cell-Permeable
The Caspase-9 Inhibitor II, Cell-Permeable controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.
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别名:
Caspase-9 Inhibitor II, Cell-Permeable, LEHD-CHO, Cell-permeable
经验公式（希尔记法）:
C97H162N22O25
分子量:
2036.46
UNSPSC代码:
12352200
NACRES:
NA.54
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质量水平
检测方案
≥95% (HPLC)
形式
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white
溶解性
DMSO: 5 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A potent, cell-permeable and reversible inhibitor or caspase-9.
A potent, cell-permeable, and reversible inhibitor of caspase-9. May also inhibit caspase-4 and caspase-5. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.
生化/生理作用
Cell permeable: yes
Product does not compete with ATP.
Reversible: yes
警告
Toxicity: Standard Handling (A)
序列
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-His-Asp-CHO
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Aditi A Kapasi et al.
Immunology, 108(3), 313-320 (2003-02-27)
Clinical reports suggest that acute ethanol intoxication is often associated with lymphopenia. Previously, ethanol was reported to invoke thymocyte apoptosis. We studied the effect of ethanol on T cell apoptosis. In addition, we evaluated the molecular mechanism of ethanol-induced T
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