218773
Caspase-8 Inhibitor I, Cell-Permeable
The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
别名:
Caspase-8 Inhibitor I, Cell-Permeable, Granzyme B Inhibitor II, Cell-permeable, IETD-CHO, Cell-permeable
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About This Item
经验公式（希尔记法）:
C95H162N20O26
分子量:
2000.42
UNSPSC代码:
12352200
NACRES:
NA.77
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质量水平
方案
≥95% (HPLC)
表单
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
white
溶解性
DMSO: 5 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A potent, cell-permeable, and reversible inhibitor of caspase-8 and Granzyme B. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.
Potent, cell-permeable and reversible inhibitor of caspase-8 and Granzyme B.
生化/生理作用
Cell permeable: yes
Primary Target
caspase-8
caspase-8
Product does not compete with ATP.
Reversible: yes
警告
Toxicity: Standard Handling (A)
序列
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Hamada, E., et al. 1990. J. Hepatol. 30, 807.
Hamada, E., et al. 1990. J. Hepatol. 30, 807.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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