218757
Caspase-6 Inhibitor I
The Caspase-6 Inhibitor I controls the biological activity of Caspase-6. This small molecule/inhibitor is primarily used for Cancer applications.
别名:
Caspase-6 Inhibitor I, Z-VE(OMe)ID(OMe)-FMK
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About This Item
经验公式（希尔记法）:
C31H45FN4O10
分子量:
652.71
UNSPSC代码:
12352200
质量水平
方案
≥90% (TLC)
表单
lyophilized solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated
溶解性
DMSO: 5 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A cell-permeable, irreversible inhibitor of caspase-6 (Mch-2).
A cell-permeable, irreversible inhibitor of caspase-6. When using with purified native or recombinant enzyme, pretreatment with an esterase is required.
生化/生理作用
Cell permeable: yes
Primary Target
caspase-6
caspase-6
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Z-Val-Glu(OMe)-Ile-Asp(OMe)-CH₂F*
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Hazel Stewart et al.
iScience, 26(11), 108080-108080 (2023-10-20)
The SARS-CoV-2 genome encodes a multitude of accessory proteins. Using comparative genomic approaches, an additional accessory protein, ORF3c, has been predicted to be encoded within the ORF3a sgmRNA. Expression of ORF3c during infection has been confirmed independently by ribosome profiling.
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