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产品名称
Caspase-5 Inhibitor I, Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.
质量水平
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated
颜色
white
溶解性
DMSO: 5 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
生化/生理作用
Cell permeable: yes
Primary Target
caspase-1, caspase-4, caspase-5, caspase-8
caspase-1, caspase-4, caspase-5, caspase-8
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
分析说明
single spot by TLC
其他说明
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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