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质量水平
方案
≥98% (HPLC)
表单
lyophilized solid
powder
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated
颜色
white to off-white
溶解性
20% acetonitrile: 1 mg/mL
运输
ambient
储存温度
−20°C
SMILES字符串
ClCC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(=O)O)CCC(=O)O)C(C)C)CC(=O)O
InChI
1S/C21H31ClN4O11/c1-9(2)18(21(37)25-12(6-16(31)32)14(28)8-22)26-19(35)11(4-5-15(29)30)24-20(36)13(7-17(33)34)23-10(3)27/h9,11-13,18H,4-8H2,1-3H3,(H,23,27)(H,24,36)(H,25,37)(H,26,35)(H,29,30)(H,31,32)(H,33,34)/t11-,12-,13-,18-/m0/s1
InChI key
ATNOUPFYBMVFLD-RSLFNQERSA-N
一般描述
A potent cell-permeable and irreversible inhibitor of caspase-3, a member of the ICE-CED-3 family of cysteine proteases.
A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10.
生化/生理作用
Cell permeable: yes
Primary Target
caspase-3, caspase-6, caspase-7, caspase-8, caspase-10
caspase-3, caspase-6, caspase-7, caspase-8, caspase-10
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Ac-Asp-Glu-Val-Asp-CMK
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
其他说明
Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197
Schrantz, N., et al. 1999. Cell Death Differ. 6, 445.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Schrantz, N., et al. 1999. Cell Death Differ. 6, 445.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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