推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
UCHT1, monoclonal
方案
>95% (immunoglobulin, SDS-PAGE)
表单
liquid
包含
0.5 mg/mL gentamycin sulfate as preservative
种属反应性
human
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
同位素/亚型
IgG1
运输
wet ice
储存温度
2-8°C
靶向翻译后修饰
unmodified
一般描述
抗CD3,小鼠单克隆,克隆UCHT1,可识别人外周T细胞中CD3复合物的ε-链。已针对冰冻切片的FC,IP,IHC和T细胞共刺激进行了验证。
蛋白A纯化的小鼠单克隆抗体。识别CD3 T细胞受体复合物的~20 kDaε链。
识别人外周T细胞中CD3复合物的ε-链。可用于激活表达CD3ε的T细胞。
免疫原
人胸腺细胞/Sezary T细胞
应用
流式细胞术(5 µg/ml)
冷冻切片(参见备注)
免疫沉淀法(参见备注)
T细胞共刺激(参见应用参考)
冷冻切片(参见备注)
免疫沉淀法(参见备注)
T细胞共刺激(参见应用参考)
包装
请参考特定浓度批号的标签。
警告
毒性:标准处理(A)
其他说明
Thibault, G. and Bardos, P. 1995.J. Immunol.154, 3814.
Beverley, P.C., and Callard, R.E.1981.Eur. J. Immunol.11, 329.
Beverley, P.C., and Callard, R.E.1981.Eur. J. Immunol.11, 329.
该抗体可用于激活表达CD3ε的T细胞(见应用参考)。对5×105培养的HPB-MLT人肿瘤细胞进行FACS。当与二级试剂山羊抗小鼠IgG(FITC偶联)一起使用时,测试的最佳结合浓度为5 µg/mL。据报道,该抗体可用于免疫沉淀和冷冻切片染色。合适的工作稀释度由与测定条件相关的变量决定。
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品?
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
American journal of cancer research, 13(11), 5218-5235 (2023-12-07)
This research is dedicated to investigating the mechanism of programmed cell death ligand 1 (PD-L1) and tumor protein 53 target gene 1 (TP53TG1) in immune regulation of colon cancer (CC). Expressions of TP53TG1, PD-L1 and signal transducers and activators of
Frontiers in immunology, 13, 799331-799331 (2022-03-18)
Trace element iron affects T cell biology, but the knowledge about the role of iron in regulating Treg cell expansion is limited. Treg cells play an important role in keeping peripheral T cell tolerance, increasing Treg cell expansion is a
The Journal of clinical investigation, 130(7), 3717-3733 (2020-03-20)
T follicular helper (Tfh) cells are indispensable for the formation of germinal center (GC) reactions, whereas T follicular regulatory (Tfr) cells inhibit Tfh-mediated GC responses. Aberrant activation of Tfh cells contributes substantially to the pathogenesis of autoimmune diseases, such as
International journal of biological sciences, 19(16), 5160-5173 (2023-11-06)
Rosacea is a common inflammatory skin disorder mediated by the dysregulation of both keratinocytes and T cells. Here, we report that aquaporin 3 (AQP3), a channel protein that mediates the transport of water/glycerol, was highly expressed in the epidermis and
Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis.
The EMBO journal, 40(22), e108125-e108125 (2021-10-08)
Mutations in VAV1, a gene that encodes a multifunctional protein important for lymphocytes, are found at different frequencies in peripheral T-cell lymphoma (PTCL), non-small cell lung cancer, and other tumors. However, their pathobiological significance remains unsettled. After cataloguing 51 cancer-associated
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门