208922-M
CaMKII Inhibitor, CK59
The CaMKII Inhibitor, CK59, also referenced under CAS 140651-18-9, controls the biological activity of CaMKII. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
别名:
CaMKII Inhibitor, CK59, 2-(2-Hydroxyethylamino)-6-aminohexylcarbamic acid tert-butyl ester-9-isopropylpurine, CK59
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About This Item
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质量水平
方案
≥95% (HPLC)
表单
semisolid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
yellow
溶解性
DMSO: 10 mg/mL
储存温度
2-8°C
SMILES字符串
[nH]1nc(c(c1N)N=Nc2ccc(cc2)O)N
InChI
1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,16H,(H5,10,11,14,15)
InChI key
AYZRKFOEZQBUEA-UHFFFAOYSA-N
一般描述
A cell-permeable Olomoucine (Cat. Nos. 495620 & 495624) analog that acts as a CaMKII inhibitor (IC50<10 µM) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 µM) and GLUT4 membrane translocation (IC50 = 100 µM) in 3T3-L1 adipocytes.
A cell-permeable Olomoucine analog that acts as a CaMKII inhibitor (IC50<10 M) and inhibits insulin-stimulated glucose uptake (IC50 ≤5 M) and GLUT4 membrane translocation (IC50 = 100 M) in 3T3-L1 adipocytes.
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution aliquot, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Konstantopoulos, N., et al. 2007. Endocrinology, 148, 374.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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