质量水平
检测方案
≥95% (HPLC)
形式
lyophilized
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
溶解性
water: 50 mg/mL
运输
ambient
储存温度
−20°C
一般描述
A 17-residue peptide based on the calmodulin-binding domain of myosin light chain kinase (MLCK). Binds to calmodulin with high affinity (Kd = 6 pM).
A 17-residue peptide based on the calmodulin-binding domain of myosin light chain kinase (MLCK). Binds to calmodulin with high affinity (Kd = 6 pM). Inhibits calmodulin activation of MLCK-catalyzed phosphorylation of smooth muscle regulatory light chain(MLC).
生化/生理作用
Cell permeable: no
Kd = 6 pM in binding to calmodulin
Primary Target
Calmodulin
Calmodulin
Product does not compete with ATP.
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Ac-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu-NH₂
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Torok,K., et al. 1998. Biochemistry 37, 6188.
Török, K., and Trentham, D.R. 1994. Biochemistry33, 12807.
Török, K., and Trentham, D.R. 1994. Biochemistry33, 12807.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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