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Merck
CN
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文件

204897

Sigma-Aldrich

Complement C4b, Human

Complement C4b, Human, is a native, 193 kDa glycoprotein composed of the modified C4 α-chain (α′) and intact β- and γ-chains complement component.

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UNSPSC代码:
12352202
NACRES:
NA.25

质量水平

检测方案

≥95% (SDS-PAGE)

形式

liquid

不包含

preservative

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
avoid repeated freeze/thaw cycles

杂质

IgG, IgA, IgM, Factor B, Factor H, C3, ceruloplasmin, or albumin, trace

运输

wet ice

储存温度

−70°C

生化/生理作用

Complement C4b fragment is formed by the cleavage of the C4 α-chain by activated C1 enzyme. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Target surface-bound C4b acts as an important non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b, C2a). This surface-bound C4b also exhibits opsonic and immune adherence activities which are dependent on the CR1 (CD35) complement receptor found on many inflammatory cells.
ComplementC4b fragment is formed by the cleavage of the C4 α-chain by activated C1enzyme. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Target surface-bound C4b acts as an important non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b, C2a). This surface-bound C4b also exhibits opsonic and immune adherence activities which are dependent on the CR1 (CD35) complement receptor found on many inflammatory cells.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

nwg


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