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Merck
CN
所有图片(1)

文件

203995

Sigma-Aldrich

N-tert-Butyl-α-phenylnitrone

Most commonly-used free radical trap.

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别名:
N-tert-Butyl-α-phenylnitrone, PBN
经验公式（希尔记法）:
C11H15NO
CAS号:
3376-24-7
分子量:
177.24
MDL编号:
MFCD00008799
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

100

检测方案

≥98% (GC)

形式

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white

溶解性

DMSO: 10 mg/mL
water: 20 mg/mL
chloroform: 50 mg/mL

运输

ambient

储存温度

−20°C

InChI

1S/C11H15NO/c1-11(2,3)12(13)9-10-7-5-4-6-8-10/h4-9H,1-3H3

InChI key

IYSYLWYGCWTJSG-UHFFFAOYSA-N

一般描述

Most commonly used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative diseases. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
Most commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

生化/生理作用

Cell permeable: no
Primary Target
Free radical trap
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution in DMSO aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 months at -20°C. Unstable in aqueous solution; reconstitute just prior to use.

其他说明

Floyd, R.A. 1997. Adv. Pharmacol. 38, 361.
Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114.
Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam.
Floyd, R.A. 1990. FASEB J. 4, 2587.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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