推荐产品
质量水平
方案
≥70% (51V-NMR)
表单
solid
效能
14 nM IC50
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
protect from light
颜色
yellow
溶解性
water: 4 mg/mL
运输
ambient
储存温度
−20°C
一般描述
一种有效的磷酸酪氨酸磷酸酶抑制剂。激活肝癌细胞的胰岛素受体激酶（IRK）。还刺激分离的脂肪细胞中的脂肪生成。还报道了有效抑制PTEN（IC50=14 nM）。
生化/生理作用
主要靶标
PTEN
PTEN
产物不与ATP竞争。
可逆：否
细胞渗透性：否
包装
用惰性气体包装
警告
毒性：标准处理（A）
重悬
溶液中不稳定；仅在使用前进行复溶。
其他说明
Schmid, A.C., et al. 2004.FEBS Lett.566, 35.
Posner, B.I., et al. 1994.J. Biol. Chem. 269, 4596.
Posner, B.I., et al. 1994.J. Biol. Chem. 269, 4596.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Zeinab Ghezelayagh et al.
Journal of assisted reproduction and genetics, 39(8), 1739-1747 (2022-07-13)
The effect of PTEN inhibitor (Bpv(HOpic); Bpv) and mTOR activators (phosphatidic acid (PA) and propranolol (PP)), were evaluated on the activation and subsequent development of human primordial follicles in ovarian tissue culture. Slow frozen-thawed human ovarian cortical strips were incubated
Amit Kumar et al.
Molecular and cellular biology, 44(7), 261-272 (2024-06-03)
The protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1 (SHP-1) plays an important role in modulating glucose and lipid homeostasis. We previously suggested a potential role of SHP-1 in the regulation of peroxisome proliferator-activated receptor γ2 (PPARγ2) expression and
Cyrine Ben Dhaou et al.
Angiogenesis (2021-09-16)
Chemerin is a multifunctional protein initially characterized in our laboratory as a chemoattractant factor for leukocyte populations. Its main functional receptor is CMKLR1. We identified previously chemerin as an anti-tumoral factor inhibiting the vascularization of tumor grafts. We show here
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门