推荐产品
产品名称
杀稻瘟菌素S,盐酸盐,灰色产色链霉菌,
方案
≥98% (HPLC)
质量水平
表单
powder
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
颜色
white to off-white
运输
ambient
储存温度
2-8°C
SMILES字符串
Cl.N2(C=CC(=NC2=O)N)[C@@H]1O[C@@H]([C@H](C=C1)NC(=O)C[C@@H](N)CCN(C)\C(=N\[H])\N)C(=O)O
InChI
1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10-,13+,14-;/m0./s1
InChI key
YQXYQOXRCNEATG-NMQKUDMSSA-N
一般描述
在原核生物和真核生物中均可特异性抑制蛋白质合成的核苷抗生素。适合与杀稻瘟菌素S抗性质粒一起用作显性选择标记。杀稻瘟菌素抗性是由杀稻瘟菌素S脱氨酶基因(bcr)所赋予的,其可将杀稻瘟菌素S转化为无毒的脱氨基羟基衍生物。
在原核生物和真核生物中均可特异性抑制蛋白质合成的核苷抗生素。适用于选择携带有杀稻瘟菌素抗性质粒的细胞。杀稻瘟菌素抗性是由杀稻瘟菌素S脱氨酶基因(蜡状芽孢杆菌的bsr或土曲霉的BSD)所赋予的,其产物可将杀稻瘟菌素S转化为无毒的脱氨基羟基衍生物。
生化/生理作用
首要靶标
蛋白质合成
蛋白质合成
警告
毒性:高毒性(H)
重悬
溶解后,等分并冷冻保存(-20°C)。水相的储备液(pH ≤7)可在-20°C最长稳定1年。避免碱性pH。避免反复冻融;当将分装的溶液解冻后,未用完的部分应丢弃。
其他说明
Kimura, M., et al. 1994.Biochim.Biophys.Acta1219, 653.
Kimura, M., et al. 1994, Mol.Gen.Genet.242, 121.
Kojima, N., et al. 1994.J. Biol. Chem.269, 30451.
Kudo, T., et al. 1994.J. Immunol. Methods177, 17.
Sutoh, K. 1993.Plasmid30, 150.
Izumi, M., et al. 1991.Exp.Cell Res.197, 229.
Yamaguchi, H., et al. 1965.J. Biol. Chem.57, 667.
Takeuchi, S., et al. 1958.J. Antibiot.11, 1.
Kimura, M., et al. 1994, Mol.Gen.Genet.242, 121.
Kojima, N., et al. 1994.J. Biol. Chem.269, 30451.
Kudo, T., et al. 1994.J. Immunol. Methods177, 17.
Sutoh, K. 1993.Plasmid30, 150.
Izumi, M., et al. 1991.Exp.Cell Res.197, 229.
Yamaguchi, H., et al. 1965.J. Biol. Chem.57, 667.
Takeuchi, S., et al. 1958.J. Antibiot.11, 1.
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法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险声明
危险分类
Acute Tox. 1 Oral
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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