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方案
≥95% (HPLC)
表单
solid
颜色
orange
溶解性
DMSO: 50 mg/mL
一般描述
A potent, cell permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC50 = 13 nM). Also inhibits protein kinase A at much higher concentrations (IC50 = 2 μM).
生化/生理作用
Target IC50:13 nM against protein kinase C
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
法规信息
新产品
D Toullec et al.
The Journal of biological chemistry, 266(24), 15771-15781 (1991-08-25)
Staurosporine is the most potent inhibitor of protein kinase C (PKC) described in the literature with a half-maximal inhibitory concentration (IC50) of 10 nM. Nevertheless, this natural product is poorly selective when assayed against other protein kinases. In order to
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