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Merck
CN
所有图片(1)

主要文件

20-265

Sigma-Aldrich

二硫苏糖醇,1M

别名:

1.4-二巯基2,3-丁二醇, Cleland′试剂, Sputolysin

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About This Item

UNSPSC代码:
41116012
eCl@ss:
32160405
NACRES:
NA.41

表单

solution

质量水平

制造商/商品名称

Upstate®

运输

dry ice

应用

二硫苏糖醇(1M )可用作十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)上样缓冲液中的还原剂。它还可作为唾液消毒的试剂。

生化/生理作用

二硫苏糖醇(DTT),也称克莱兰试剂,是一种含有两个巯基官能团的还原剂。在蛋白质化学研究中,它可作为巯基保护剂。在化学肽合成中,DTT 可用于还原各种底物(如谷胱甘肽、蛋白和其它大分子)中的二硫键。它也可用作痰液处理的粘液溶解剂。

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Irrit. 2

储存分类代码

10 - Combustible liquids

WGK

WGK 2


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Sun Young Park et al.
Viruses, 12(12) (2020-12-11)
Although polyethylene glycol (PEG) application is the most widely used method in removing nonstructural proteins (NSPs) for foot-and-mouth disease (FMD) vaccine production, some NSPs remaining in the antigen could elicit antibodies against these proteins after repeated vaccinations in livestock. Therefore
Reza Heidari et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 99, 1022-1032 (2018-01-09)
Cholestasis is a disorder characterized by impaired bile flow and accumulation of cytotoxic bile acids in the liver. On the other hand, oxidative stress and its deleterious consequences seem to have a significant role in cholestasis-induced organ injury. Hence, antioxidants
I S Woolhouse et al.
Thorax, 57(8), 667-671 (2002-08-01)
Sputum analysis is used increasingly to assess airway inflammation in patients with chronic obstructive pulmonary disease, including those with chronic bronchitis and bronchiectasis. However, it is not known whether dithiothreitol (DTT), a reducing mucolytic agent regularly used to homogenise sputum
A Novel Dental Caries Model Replacing, Refining, and Reducing Animal Sacrifice
Wolfoviz-Zilberman A, et al.
Applied Sciences, 11(15), 7141-7141 (2021)
A Kr zel et al.
Journal of inorganic biochemistry, 84(1-2), 77-88 (2001-05-02)
D,L-Dithiothreitol (DTT), known also as Cleland reagent, is a thiol group protectant, used commonly in peptide and protein chemistry. Therefore, it is often added at high concentrations in preparations of proteins relevant to heavy metal biochemistry. The coordination of five

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