产品名称
胆红素, Principal pigment of bile and one of the major end products of hemoglobin decomposition.
SMILES string
[nH]1c(c(c(c1\C=C4/NC(=O)C(=C/4C)C=C)C)CCC(=O)O)Cc2[nH]c(c(c2CCC(=O)O)C)\C=C3/NC(=O)C(=C/3C=C)C
InChI
1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-
InChI key
BPYKTIZUTYGOLE-IFADSCNNSA-N
description
RTECS - DU3038000
Merck USA index - 14, 1218
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
red-brown
solubility
chloroform: 1 mg/mL
alkaline solution: soluble
shipped in
ambient
storage temp.
10-30°C
Quality Level
相关类别
Biochem/physiol Actions
据报道，胆红素可穿过血脑屏障，在脑中发挥重要的抗氧化作用。各种黄疸的变色症状中都有胆红素参与。胆红素水平可作为肝脏和血液病的生物标志物。低浓度的未结合胆红素可作为生理抗氧化剂，但胆红素浓度过高会产生毒性，导致新生儿高胆红素血症。
General description
胆红素是橙黄色的胆汁色素，是血红蛋白降解的主要代谢终产物之一。含有共轭双键和活泼氢原子。对于成人，正常范围内的胆红素浓度上限为>1mg/dL。新生儿的血清胆红素水平小于15 mg/dl。本品是未结合胆红素。
Other Notes
消光系数(454 nm, CHCl3)：59,100-62,300 M-1cm-1。
细胞渗透性：否
可逆：否
产物不与ATP竞争。
主要靶标
细胞渗透性：否
可逆：否
产物不与ATP竞争。
主要靶标
Preparation Note
碱性溶液中不稳定；临用前复溶。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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