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200488

Bestatin Hydrochloride

Name: Bestatin Hydrochloride
Brand: MM

InSolution, ≥98%, a metalloprotease inhibitor

别名:

InSolutionBestatin, Hydrochloride, [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl

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About This Item

经验公式（希尔记法）:

C₁₆H₂₄N₂O₄ · xHCl

分子量:

308.37 (free base basis)

UNSPSC代码:

12352202

NACRES:

NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

liquid

制造商/商品名称

Calbiochem^®

储存条件

OK to freeze
avoid repeated freeze/thaw cycles
protect from light

运输

dry ice

储存温度

−20°C

SMILES字符串

CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O.[xHCl]

一般描述

A metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.

生化/生理作用

Cell permeable: no

Primary Target
Metalloproteases

Reversible: yes

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

外形

Supplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.

重悬

Following initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

其他说明

Merck Index: 14, 9842.
Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab.79, 171.
Taylor, A., et al. 1993. Biochemistry32, 784.
Ishida, J.I., et al. 1984. J. Chromatogr.305, 381.
Umezawa, H. 1982. Annu. Rev. Microbiol.36, 75.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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