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描述
Bafilomycin A1 is a specific potent inhibitor of vacuolar-type H+-ATPases, and blocks lysosomal cholesterol transport in macrophages.
质量水平
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
储存温度
−20°C
1 of 4
此商品 | OGS621 | OGS620 | OGS619 |
|---|---|---|---|
| peptide cleavage EKT | peptide cleavage EKT | peptide cleavage EKT | peptide cleavage EKT |
| origin of replication pUC | origin of replication pUC | origin of replication pUC | origin of replication pUC |
| peptide tag location N-terminal | peptide tag location N-terminal | peptide tag location N-terminal | peptide tag location C-terminal |
| bacteria selection ampicillin | bacteria selection ampicillin | bacteria selection ampicillin | bacteria selection ampicillin |
| mol wt size 5913 bp | mol wt size 4610 bp | mol wt size 4568 bp | mol wt size 4530 bp |
应用
巴佛洛霉素A1已被用于：
- 作为自噬抑制剂用于研究其对大鼠脑创伤（TBI）引起的细胞死亡和损伤的作用
- 用于 pH luorin 测定中神经元的处理以测定突触活动中的内噬作用
- 阻止小鼠胚胎成纤维细胞中的自噬
生化/生理作用
抑制剂种类：激酶
外形
C35H58O9
储存及稳定性
在-20°C下可保存3年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
法规信息
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