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Merck
CN
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文件

189725

Sigma-Aldrich

亲和素,蛋白

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别名:
亲和素,蛋白
CAS号:
MDL编号:
UNSPSC代码:
41116133
NACRES:
NA.41

形式

lyophilized solid

质量水平

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

颜色

white

溶解性

dilute buffer: 5 mg/mL
distilled water: 5 mg/mL

运输

ambient

储存温度

−20°C

一般描述

亲和素是一种四聚体糖蛋白,是所有卵生脊椎动物的卵中的一种抗营养物质。其占鸡蛋总蛋白的0.05–0.5%。亲和素结构包含八个正交反平行β链、一个二硫键和一个糖基侧链。

应用

蛋白亲和素已被用作蛋白质结合试验中的阻断剂。它也被用于形成亲和素-生物素连接,将吉西他滨结合到微泡上,以便给药到体内模型中。

生化/生理作用

亲和素可用作抗体、荧光染料、蛋白质以及其他生物化学家感兴趣的分子标记物。亲和素与生物素(维生素H)具有高结合亲和力,可导致微生物无法获得生物素,从而抑制其增殖。亲和素的这一特性有助于其抗菌特性,并影响生物素在体内的吸收,导致维生素B7缺乏。

警告

毒性:标准处理(A)

单位定义

一个单位定义为在pH 8.9条件下,结合1 µg D-生物素所需的亲和素的量。

重悬

在复溶后存放于冰箱(4°C)。储备液在4°C条件下可稳定保存6个月。避免冻/融循环。

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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