189513
Autotaxin Inhibitor IV, HA155
The Autotaxin Inhibitor IV, HA155 controls the biological activity of Autotaxin. This small molecule/inhibitor is primarily used for Cell Structure applications.
别名:
Autotaxin Inhibitor IV, HA155, Atx Inhibitor IV, HA155, ( Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid, Atx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid
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About This Item
推荐产品
质量水平
方案
≥99% (HPLC)
表单
powder
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
protect from light
颜色
yellow
溶解性
DMSO: 100 mg/mL
运输
ambient
储存温度
−20°C
SMILES字符串
O=C(/C(S1)=C/C2=CC=C(OCC3=CC=C(B(O)O)C=C3)C=C2)N(CC4=CC=C(F)C=C4)C1=O
InChI key
BRWUZCBSWABPMR-XKZIYDEJSA-N
一般描述
A ~5-fold more potent (IC50 = 5.7 nM) para-isomer boronate analog of Autotaxin Inhibitor II, HA130 (Cat. No. 189511) that efficiently blocks thrombin-stimulated lysophosphatidic acid secretion in platelets and in mammalian cells.
包装
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Fulkerson, Z., et al. 2011. J. Biol. Chem.286, 34654.
Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol.18, 198.
Albers, H.M.H.G., et al. 2011. J. Med. Chem.54, 4619.
Albers, H.M.H.G., et al. 2010. J. Med. Chem.53, 4958.
Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol.18, 198.
Albers, H.M.H.G., et al. 2011. J. Med. Chem.54, 4619.
Albers, H.M.H.G., et al. 2010. J. Med. Chem.53, 4958.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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