推荐产品
生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
liquid
包含
≤0.1% sodium azide as preservative
种属反应性
human
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
同位素/亚型
IgG
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
一般描述
Anti-Apolipoprotein A-I, rabbit polyclonal, recognizes human apolipoprotein A-I. Does not cross-react with other apolipoproteins. It is validated for ELISA and Western blotting.
Rabbit polyclonal antibody purified by ammonium sulfate precipitation and DEAE-cellulose ion exchange chromatography. Recognizes the apolipoprotein A-I protein.
Recognizes human apolipoprotein A-I. Does not cross-react with other human apolipoproteins.Antibody Target Gene Symbol: APOA1 Target Synonym: Ai, ALP-1, Apo1a, APOA-I, APOLIPOPROTEIN A-I, APOLIPOPROTEIN A-I G1, APOLIPOPROTEIN A1, Brp-14, HDLA1, LP(A-I), Ltw-1, Lvtw-1, MGC102525, MGC117399, Sep-1, Sep-2 Entrez Gene Name: apolipoprotein A-I Hu Entrez ID: 335 (Related Antibodies: 178474, 178472, 178470, 178463) Mu Entrez ID: 11806 Rat Entrez ID: 25081
免疫原
Human
full length, human apolipoprotein A-I
应用
ELISA (≥1:800)
Immunoblotting (1:1000)
Immunoblotting (1:1000)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
外形
In PBS.
重悬
Following initial thaw, aliquot and freeze (-20°C).
其他说明
Does not cross-react with Apolipoprotein A-II, B, C-I, C-II, C-III or E by immunoblotting. Variables associated with assay conditions will dictate the proper working dilution.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Elias N Glaros et al.
Journal of lipid research, 49(2), 324-331 (2007-11-06)
The serine palmitoyl transferase inhibitor myriocin potently suppresses the development of atherosclerosis in apolipoprotein E (apoE) gene knockout (apoE(-/-)) mice fed a high-fat diet. This is associated with reduced plasma sphingomyelin (SM) and glycosphingolipid levels. Furthermore, oral administration of myriocin
John T Melchior et al.
Journal of lipid research, 58(7), 1374-1385 (2017-05-10)
HDLs are a family of heterogeneous particles that vary in size, composition, and function. The structure of most HDLs is maintained by two scaffold proteins, apoA-I and apoA-II, but up to 95 other "accessory" proteins have been found associated with
W Sean Davidson et al.
Journal of lipid research, 57(4), 674-686 (2016-02-26)
HDL cholesterol (HDL-C) efflux function may be a more robust biomarker of coronary artery disease risk than HDL-C. To study HDL function, apoB-containing lipoproteins are precipitated from serum. Whether apoB precipitation affects HDL subspecies composition and function has not been
Roshni R Singaraja et al.
Circulation, 114(12), 1301-1309 (2006-08-31)
Extrahepatic tissues have long been considered critical contributors of cholesterol to nascent HDL particles in the reverse cholesterol transport pathway, in which ABCA1 plays the crucial role. Recent studies, however, including both overexpression and deletion of ABCA1 selectively in the
Elena Thomàs-Moyà et al.
Journal of lipid research, 47(9), 2042-2048 (2006-07-04)
Caloric restriction (CR) has been shown to attenuate age-related oxidative damage and to improve major atherosclerotic risk factors. Paraoxonase 1 (PON1), an enzyme specifically associated with HDL containing apolipoproteins A-I and J, has been reported to prevent the proatherosclerotic effects
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