产品名称
Anti-Angiopoietin-2 Rabbit pAb, liquid, Calbiochem®
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
does not contain
preservative
species reactivity
mouse
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(ELISA (0.1-1 µg/mL)
Immunoblotting (1-10 µg/mL)
Immunofluorescence (2-20 µg/mL)
Immunohistochemistry (2-20 µg/mL))
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Application
ELISA (0.1-1 µg/ml)
Immunoblotting (1-10 µg/ml)
Immunofluorescence (2-20 µg/ml)
Immunohistochemistry (2-20 µg/ml)
Immunoblotting (1-10 µg/ml)
Immunofluorescence (2-20 µg/ml)
Immunohistochemistry (2-20 µg/ml)
Disclaimer
Toxicity: Standard Handling (A)
General description
Anti-Angiopoietin-2, rabbit polyclonal, recognizes the ~55 kDa non-glycosylated and the ~70 kDa glycosylated, secreted Ang-2 protein. It is validated for ELISA, WB, IF, and IHC.
Immunoaffinity purified rabbit polyclonal antibody. Recognizes both the ~55 kDa nonglycosylated and the ~70 kDa glycosylated forms of angiopoietin-2.
Recognizes both the ~55 kDa non-glycosylated and the ~70 kDa glycosylated, secreted Ang-2 protein in cell culture medium. Does not cross-react with Ang-1.Antibody Target Gene Symbol: ANGPT2 Target Synonym: AGPT2, ANG II, ANG-2, ANGIOPOIETIN, ANGIOPOIETIN 2, Angiotensin 2, Angrp Entrez Gene Name: angiopoietin 2 Hu Entrez ID: 285 Mu Entrez ID: 11601 Rat Entrez ID: 89805
Immunogen
a synthetic peptide corresponding to a 21 amino acid cytoplasmic sequence at the N-terminus of mouse angiopoietin-2
Other Notes
Maisonpierre, P.C., et al. 1997. Science 277, 55.
Davis, S., et al. 1996. Cell 87, 1161.
Suri, S. et al. 1996. Cell 87, 1171.
Davis, S., et al. 1996. Cell 87, 1161.
Suri, S. et al. 1996. Cell 87, 1171.
The immunogenic peptide sequence is 71% (15/21 amino acids) conserved in the human angiopoietin-2 protein. Does not cross-react with angiopoietin-1. Variables associated with assay conditions will dictate the optimal working dilution.
Packaging
Please refer to vial label for lot-specific concentration.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Angara Sureshbabu et al.
Respiratory research, 16, 4-4 (2015-01-17)
Earlier studies have reported that transforming growth factor beta 1(TGFβ1) is a critical mediator of hyperoxia-induced acute lung injury (HALI) in developing lungs, leading to impaired alveolarization and a pulmonary phenotype of bronchopulmonary dysplasia (BPD). However, the mechanisms responsible for
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