质量水平
制造商/商品名称
Upstate®
技术
activity assay: suitable
affinity binding assay: suitable
NCBI登记号
UniProt登记号
运输
dry ice
基因信息
human ... RAP1GDS1(5910)
包装
Kit capacity: 20-30 assays
组分
100X GTPγS, 10mM (Cat.# 20-176)
100X GDP, 100mM (Cat.# 20-177)
Rap1 Activation Lysis Buffer, 2X
Anti-Rap1
Rap1 Assay Reagent (Ral GDS-RBD, agarose) (Cat.# 14-455)
100X GDP, 100mM (Cat.# 20-177)
Rap1 Activation Lysis Buffer, 2X
Anti-Rap1
Rap1 Assay Reagent (Ral GDS-RBD, agarose) (Cat.# 14-455)
质量
Routinely evaluated by affinity precipitation assay. Ral GDS RBD, agarose precipitated GTP-Rap1 from HEK293 lysates. The precipitated GTP-Rap1 was detected by immunoblot analysis using Anti-Rap1.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
WGK
WGK 2
Uma Potla et al.
The Journal of clinical investigation, 124(4), 1757-1769 (2014-03-20)
Injury to the specialized epithelial cells of the glomerulus (podocytes) underlies the pathogenesis of all forms of proteinuric kidney disease; however, the specific genetic changes that mediate podocyte dysfunction after injury are not fully understood. Here, we performed a large-scale
Xi Su et al.
Cell death & disease, 13(3), 218-218 (2022-03-11)
Thyroid cancer (TC) is one of the most common malignancies involving the head and neck, and its incidences are increasing every year. Small G protein signaling modulators 2 (SGSM2) belongs to a newly identified protein group that contributes to numerous
Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
Herrmann, C, et al
The Journal of Biological Chemistry, 271, 6794-6800 (1996)
Rasmus Koefoed Petersen et al.
Molecular and cellular biology, 28(11), 3804-3816 (2008-04-09)
Cyclic AMP (cAMP)-dependent processes are pivotal during the early stages of adipocyte differentiation. We show that exchange protein directly activated by cAMP (Epac), which functions as a guanine nucleotide exchange factor for the Ras-like GTPases Rap1 and Rap2, was required
Emilie Montenont et al.
Blood advances, 5(9), 2362-2374 (2021-05-05)
Human anucleate platelets cannot be directly modified using traditional genetic approaches. Instead, studies of platelet gene function depend on alternative models. Megakaryocytes (the nucleated precursor to platelets) are the nearest cell to platelets in origin, structure, and function. However, achieving
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