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Merck
CN
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文件

17-300

Sigma-Aldrich

Ral Activation Assay Kit

Non-radioactive Ral Activation Assay Kit can be used to precipitate Ral-A-GTP from cell lysates & detection by a Ral-A specific antibody.

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UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

制造商/商品名称

Upstate®

技术

activity assay: suitable
affinity binding assay: suitable

NCBI登记号

UniProt登记号

运输

dry ice

基因信息

human ... RALA(5898)

包装

Kit capacity: 30 assays

组分

Ral Activation Assay Buffer, 5X (Cat.# 20-196)

100X GTPγS, 10mM (Cat.# 20-176)

100X GDP, 100mM (Cat.# 20-177)

Anti-Ral-A

Ral Assay Reagent (Ral BP1, agarose) (Cat.# 14-415)

质量

Routinely evaluated by affinity precipitation/immunoblot analysis. Ral-A-GTP was precipitated from EGF-stimulated Cos-7 cell lysates. The precipitated Ral-A-GTP was detected by Western immunoblot analysis using anti-Ral A.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Aquatic Chronic 3 - Eye Dam. 1

WGK

WGK 3


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Elena Tchevkina et al.
Oncogene, 24(3), 329-335 (2004-10-07)
RAS oncogenes play a critical role in oncogenic transformation and metastases formation. Here we show that Ha-ras greatly stimulates spontaneous metastatic activity of transformed cells through the Ras/RalGDS/RalA intracellular signaling pathway. Introduction of RalA alone leads to a drastic increase
2'-Methylseleno-modified oligoribonucleotides for X-ray crystallography synthesized by the ACE RNA solid-phase approach.
Barbara Puffer,Holger Moroder,Michaela Aigner,Ronald Micura
Nucleic Acids Research null
M C Araujo et al.
Biochemistry, 39(29), 8519-8525 (2000-07-29)
Quenched fluorescence peptides were used to investigate the substrate specificity requirements for recombinant wild-type angiotensin I-converting enzyme (ACE) and two full-length mutants bearing a single functional active site (N- or C-domain). We assayed two series of bradykinin-related peptides flanked by
Nicolas Personnic et al.
The FEBS journal, 281(13), 2977-2989 (2014-05-13)
Ral proteins are small GTPases that play critical roles in normal physiology and in oncogenesis. There is little information on the GTPase-activating proteins (GAPs) that downregulate their activity. Here, we provide evidence that the noncatalytic β subunit of RalGAPα1/2 β
M Foschi et al.
The EMBO journal, 16(21), 6439-6451 (1997-11-14)
Endothelin-1 (ET-1) induces cell proliferation and differentiation through multiple G-protein-linked signaling systems, including p21ras activation. Whereas p21ras activation and desensitization by receptor tyrosine kinases have been extensively investigated, the kinetics of p21ras activation induced by engagement of G-protein-coupled receptors remains

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