17-283
Rac1活化测定试剂盒
Non-radioactive Rac1 Activation Assay Kit can be used to precipitate Rac1-GTP from cell lysates & detection by a Rac1 specific monoclonal antibody.
别名:
Activation Assay Kit, Rac1 Activity Kit, Rac1 Assay Kit
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About This Item
UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.32
推荐产品
质量水平
种属反应性
human, rat, mouse
制造商/商品名称
Upstate®
技术
activity assay: suitable
affinity binding assay: suitable
UniProt登记号
运输
dry ice
基因信息
human ... RAC1(5879)
一般描述
非放射性Rac1活化测定试剂盒可用于沉淀细胞裂解物中的Ras相关C3肉毒杆菌毒素底物1 (Rac1)-GTP,并通过Rac1特异性单克隆抗体检测。Rac1属于小鸟苷三磷酸酶(GTPases)的Ras超级家族。它以两种主要形式表达,即非活性GDP结合形式和活性GTP结合形式。Rac1通过与激活多种信号级联的效应物相互作用,参与影响多种生理条件。RAC1基因位于人染色体7p22.1。
应用
Rac1激活测定试剂盒已用于通过免疫印迹法检测小鼠和人脑匀浆中的活性Ras相关C3肉毒杆菌毒素底物1 (Rac1)。
组分
抗Rac1,克隆23A8(目录号05-389)
Mg2+裂解/洗涤缓冲液,5X(目录号20-168)
100X GTPγS,10mM(目录号20-176)
100X GDP,100mM(目录号20-177)
Rac/Cdc42测定试剂(PAK1 PBD,琼脂糖)(目录号14-325)
Mg2+裂解/洗涤缓冲液,5X(目录号20-168)
100X GTPγS,10mM(目录号20-176)
100X GDP,100mM(目录号20-177)
Rac/Cdc42测定试剂(PAK1 PBD,琼脂糖)(目录号14-325)
质量
通过从已加载GTPγS的3T3细胞裂解物中沉淀Rac-GTP进行常规评估。 使用抗Rac通过免疫印迹分析检测沉淀的Rac-GTP。
联系
替代:SGT425
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
储存分类代码
10 - Combustible liquids
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