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一般描述
肌肉RAS癌基因同源物（MRAS）在心血管疾病中起关键作用。该MRAS基因编码GTP结合蛋白的ras超家族的一员。MRAS存在于所有组织中，特别是心血管系统中。它参与信号转导，包括细胞生长和分化。
包装
试剂盒容量：30次测定
组分
Ras检测试剂（Raf-1 RBD，琼脂糖）（目录号14-278）
Anti-Ras，克隆RAS10（目录号05-516）
100X GTPγS，10mM（目录号20-176）
100X GDP，100mM（目录号20-177）
Mg2+裂解/洗涤缓冲液，5X（目录号20-168）
Anti-Ras，克隆RAS10（目录号05-516）
100X GTPγS，10mM（目录号20-176）
100X GDP，100mM（目录号20-177）
Mg2+裂解/洗涤缓冲液，5X（目录号20-168）
质量
该试剂盒从已装有GTPγS的HeLa细胞裂解物中沉淀出Ras-GTP。使用1 μg/ml抗Ras克隆RAS10通过蛋白质免疫印迹检测沉淀的Ras-GTP
联系
替代：SGT435
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
警示用语：
Danger
危险声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
储存分类代码
10 - Combustible liquids
法规信息
常规特殊物品
Shin-Ichiro Miura et al.
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Since we recently demonstrated that high-density lipoprotein induced human coronary artery endothelial cell (HCEC) tube formation through Ras/Raf/ERK (extracellular-signal-regulated kinase) activation [Arterioscler. Thromb. Vasc. Biol. 23 (2003) 802], it is possible that lipid-lowering agents such as statins, which reduce the
Richard J Calvert et al.
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Accurate measurement of activity of wild-type K-ras protein is important due to its tumor suppressor action in tissues such as lung. A published method by Taylor and co-workers uses plasmid-containing Escherichia coli cells to produce a glutathione-S-transferase/raf-1 ras binding domain
Shin-ichiro Miura et al.
Biochemical and biophysical research communications, 306(4), 924-929 (2003-06-25)
Since we recently reported that high density lipoprotein, which contains the bioactive lipid sphingosine-1-phosphate (S1P) [Arterioscler. Thromb. Vasc. Biol. 23 (2003) 802], induced human coronary artery endothelial cell (HCEC) tube formation mediated by a Ras/Raf/ERK (extracellular signal-activated kinase) pathway, we
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Interleukin 1beta (IL-1beta) suppresses the IL-6-dependent induction of type II acute-phase response genes, but the underlying mechanism for this suppression remains uncertain. Here we report that treatment of human hepatocullular carcinoma HepG2 cells with IL-1beta inhibited the IL-6-dependent binding of
AnhCo Nguyen et al.
Molecular and cellular biology, 22(9), 3035-3045 (2002-04-10)
While scaffold proteins are thought to be key components of signaling pathways, their exact function is unknown. By preassembling multiple components of signaling cascades, scaffolds are predicted to influence the efficiency and/or specificity of signaling events. Here we analyze a
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Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.
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