推荐产品
质量水平
制造商/商品名称
Upstate®
技术
activity assay: suitable (phosphatase)
NCBI登记号
UniProt登记号
检测方法
colorimetric
运输
wet ice
基因信息
human ... PPP2R1B(5519)
应用
Ser/Thr磷酸酶检测试剂盒1用于通过磷酸肽的去磷酸化来检测PP2A活性。
用于检测/量化：Ser/Thr激酶
包装
试剂盒容量：100次测定
组分
孔雀石绿溶液A（目录号20-105）
孔雀石绿添加剂（目录号20-104）
磷酸盐标准品（目录号20-103）
苏氨酸磷酸肽（K-R-pT-I-R-R）（目录号12-219）
pNPP（对硝基苯基磷酸盐）（目录号20-106）
pNPP Ser/Thr分析缓冲液（目录号20-179）
NiCl2，40mM（目录号20-178）
96孔微量滴定板
孔雀石绿添加剂（目录号20-104）
磷酸盐标准品（目录号20-103）
苏氨酸磷酸肽（K-R-pT-I-R-R）（目录号12-219）
pNPP（对硝基苯基磷酸盐）（目录号20-106）
pNPP Ser/Thr分析缓冲液（目录号20-179）
NiCl2，40mM（目录号20-178）
96孔微量滴定板
质量
通常用于通过磷酸肽（K-R-pT-I-R-R）的去磷酸化或pNPP的水解来检测PP2A（目录号14-111）活性
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
警示用语：
Danger
危险分类
Aquatic Chronic 3 - Carc. 1A Inhalation - Met. Corr. 1 - Repr. 1B - Skin Sens. 1 - STOT RE 2
靶器官
Lungs
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
法规信息
常规特殊物品
Anna Signorile et al.
FEBS letters, 512(1-3), 91-94 (2002-02-20)
Immunochemical and functional evidence showing the existence in the inner membrane and matrix fraction of mammalian mitochondria of serine/threonine phosphatases acting on cAMP-dependent phosphoproteins is presented. Mg(2+)-dependent Ca(2+)-inhibitable PP2C phosphatase, associated to the inner membrane, dephosphorylates the 18 kDa (NDUFS4
Usha Narayanan et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(52), 14349-14357 (2007-12-28)
Fragile X syndrome is a common form of inherited mental retardation and is caused by loss of fragile X mental retardation protein (FMRP), a selective RNA-binding protein that influences the translation of target messages. Here, we identify protein phosphatase 2A
Roumen Pankov et al.
The Journal of biological chemistry, 278(20), 18671-18681 (2003-03-15)
Integrin transmembrane receptors generate multiple signals, but how they mediate specific signaling is not clear. Here we test the hypothesis that particular sequences along the beta(1) integrin cytoplasmic domain may exist that are intimately related to specific integrin-mediated signaling pathways.
Katsuo Suzuki et al.
International journal of oncology, 23(5), 1263-1268 (2003-10-09)
The beta1 subunit of integrin is serine/threonine phosphorylated in growth arrested human breast cancer MCF-7 cells, while it is not in quiescent normal human breast epithelial (HBE) cells. Using the affinity-purified antibodies PB788-9 against the synthetic oligopeptide that contained phosphothreonines
Michael E Price et al.
American journal of physiology. Lung cellular and molecular physiology, 308(6), L577-L585 (2015-01-13)
Airway mucociliary clearance is a first-line defense of the lung against inhaled particles and debris. Among individuals with alcohol use disorders, there is an increase in lung diseases. We previously identified that prolonged alcohol exposure impairs mucociliary clearance, known as
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