生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
4G12, monoclonal
种属反应性（根据同源性预测）
all
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
运输
wet ice
靶向翻译后修饰
acetylation (Lys)
特异性
识别含乙酰赖氨酸的蛋白质，包括组蛋白。
免疫原
化学乙酰化抗原的混合物。 克隆4G12。
应用
用抗乙酰赖氨酸抗体（克隆4G12，琼脂糖偶联物，小鼠单克隆抗体）检测乙酰赖氨酸，该抗体已被证明可在IP中起作用。
研究亚类
常规翻译后修饰
组蛋白
常规翻译后修饰
组蛋白
研究类别
信号传导
表观遗传学&核功能
信号传导
表观遗传学&核功能
特点和优势
形式：凝胶固定
质量
通过免疫沉淀进行了常规评估。
目标描述
因检测的蛋白质而异。
储存及稳定性
自发货之日起在4°C下可保存1年。不可冷冻。
其他说明
浓度：请参考批次特异性浓缩物的检验报告。
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Yan Liu et al.
Journal of proteome research, 20(5), 2596-2606 (2021-04-02)
Decreased cellular NAD+ levels are causally linked to aging and aging-associated diseases. NAD+ precursors in oxidized form such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) have gained much attention and been well studied for their ability to restore NAD+
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Methods in enzymology, 573, 161-181 (2016-07-04)
Histone deacetylase assays were first developed in the 1970s, and subsequently refined in the 1990s with the cloning of HDAC enzymes. Most of these early assays, relying on traditional in vitro chemical methodologies, are still applicable today. More recently, however
Acetylation of general transcription factors by histone acetyltransferases.
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The transcriptional coactivators CBP and P/CAF are required for activation of transcription from the IFN beta enhanceosome. We show that CBP and P/CAF acetylate HMG I(Y), the essential architectural component required for enhanceosome assembly, at distinct lysine residues, causing distinct
Fei Yue et al.
Aging, 7(10), 839-853 (2015-11-06)
Autophagy controls and executes the turnover of abnormally aggregated proteins. MAP1S interacts with the autophagy marker LC3 and positively regulates autophagy flux. HDAC4 associates with the aggregation-prone mutant huntingtin protein (mHTT) that causes Huntington's disease, and colocalizes with it in
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