一般描述
意义:
抗磷脂酰丝氨酸可用于检测膜磷脂磷脂酰丝氨酸(PS)从内膜小叶向外膜小叶的移位;它提供了膜联蛋白V的替代方法,用于定量细胞凋亡。
抗磷脂酰丝氨酸可用于检测膜磷脂磷脂酰丝氨酸(PS)从内膜小叶向外膜小叶的移位;它提供了膜联蛋白V的替代方法,用于定量细胞凋亡。
磷脂酰丝氨酸或PS是天然存在的磷脂营养素。PS对所有人体细胞的功能至关重要,但最集中在大脑中。它在该器官中的相对丰度反映了它已被证明参与了各种神经细胞功能,包括神经递质释放和突触活性。临床研究表明,PS可以支持随着年龄增长而下降的大脑功能。
特异性
识别细胞膜中的磷脂酰丝氨酸(PS)
免疫原
含有70%磷脂酰丝氨酸和30%磷脂酰甘油的脂质体。
应用
使用经验证可用于FC的抗磷脂酰丝氨酸抗体(克隆1H6,Alexa Fluor 488)检测磷脂酰丝氨酸。
研究子类别
凋亡-附加
凋亡-附加
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
质量
流式细胞术: 0.2 μg该抗体可在固定Jurkat细胞中检测出磷脂酰丝氨酸(见第2页)。
凋亡测定:使用抗磷脂酰丝氨酸,克隆1H6,Alexa Fluor™ 488偶联物或膜联蛋白V FITC偶联物测量星形孢菌素对Jurkat细胞中凋亡诱导的时间过程。
凋亡测定:使用抗磷脂酰丝氨酸,克隆1H6,Alexa Fluor™ 488偶联物或膜联蛋白V FITC偶联物测量星形孢菌素对Jurkat细胞中凋亡诱导的时间过程。
外形
纯化的小鼠单克隆IgG,溶于含有PBS、1% BSA、0.05%吐温和0.05%叠氮化钠的缓冲液中。 在4ºC为液体形式。
蛋白G纯化
储存及稳定性
自收到之日起可稳定保存1年。
分析说明
对照
阴性对照:目录号16-240,正常小鼠IgG,Alexa Fluor™ 488-偶联物。
阴性对照:目录号16-240,正常小鼠IgG,Alexa Fluor™ 488-偶联物。
其他说明
浓度:请参考批次特异性浓缩物的检验报告。
法律信息
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Alexa Fluor™是Molecular Probes, Inc.的注册商标。
除非在产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得对人或动物用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用。
除非在产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得对人或动物用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用。
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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