产品名称
Anti-FAK Antibody, clone 4.47, Alexa Fluor™ 555 conjugate, clone 4.47, Upstate®, from mouse
biological source
mouse
conjugate
ALEXA FLUOR™ 555
antibody form
purified antibody
antibody product type
primary antibodies
clone
4.47, monoclonal
species reactivity
rat, mouse, human
manufacturer/tradename
Upstate®
technique(s)
flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PTK2(5747)
Analysis Note
Control
Negative Control: Catalog # 16-240, Normal Mouse IgG, ALEXA FLUOR™ 488-conjugate.
Negative Control: Catalog # 16-240, Normal Mouse IgG, ALEXA FLUOR™ 488-conjugate.
Routinely evaluated by immunostaining in 3T3 cells
Application
Anti-FAK Antibody, clone 4.47, Alexa Fluor 555 conjugate detects level of FAK & has been published & validated for use in FC, WB & IC.
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
Biochem/physiol Actions
p125FAK, does not cross react with Pyk-2
Disclaimer
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
125kDa
Immunogen
GST fusion protein corresponding to residues 1-423 of human FAK (focal adhesion kinase)
Physical form
Protein G Purified
Preparation Note
1 year at 4°C from date of shipment
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Advances in high content screening for drug discovery.
Giuliano, Kenneth A, et al.
Assay and Drug Development Technologies, 1, 565-577 (2003)
Jana Harizanova et al.
PloS one, 11(8), e0160591-e0160591 (2016-08-16)
Integrin adhesome proteins bind each other in alternative manners, forming within the cell diverse cell-matrix adhesion sites with distinct properties. An intriguing question is how such modular assembly of adhesion sites is achieved correctly solely by self-organization of their components.
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