推荐产品
生物来源
mouse
质量水平
偶联物
ALEXA FLUOR™ 488
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
4.47, monoclonal
种属反应性
human, rat, mouse
制造商/商品名称
Upstate®
技术
flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... PTK2(5747)
特异性
p125FAK, does not cross react with Pyk-2
免疫原
GST fusion protein corresponding to residues 1-423 of human FAK (focal adhesion kinase)
应用
Detect FAK using this Anti-FAK Antibody, clone 4.47, Alexa Fluor 488 conjugate validated for use in FC, WB & IC.
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
质量
Routinely evaluated by immunostaining of 3T3 cells.
目标描述
125kDa
外形
Protein G Purified
储存及稳定性
1 year at 4°C from date of shipment
法律信息
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Focal adhesion kinase: in command and control of cell motility.
Mitra, Satyajit K, et al.
Nature Reviews in Molecular and Cell Biology, 6, 56-68 (2005)
Steven K Hanks et al.
Frontiers in bioscience : a journal and virtual library, 8, d982-d996 (2003-04-18)
Focal adhesion kinase (FAK) was first described in 1992 as a novel nonreceptor protein-tyrosine kinase localized prominently within focal adhesions, suggesting a signaling role in regulating cell behavior resulting from integrin interaction with the extracellular matrix. Subsequent studies over the
Nam Cong-Nhat Huynh et al.
PloS one, 11(7), e0159843-e0159843 (2016-07-22)
Rinsing the mouth with sodium chloride (NaCl) solution is believed to promote healthy gum and improve oral ulcer healing. Scientific evidence to support this assumption is, however, lacking. This study aims to investigate the effect and clarify underlying mechanisms of
Focal adhesion kinase: the first ten years.
Parsons, J Thomas
Journal of Cell Science, 116, 1409-1416 (2003)
David D Schlaepfer et al.
Current opinion in genetics & development, 14(1), 92-101 (2004-04-28)
The ability of intracellular signaling networks to orchestrate a complex biological response such as cell motility requires that individual signaling proteins must act as integrators, responding to multiple extracellular inputs and regulating multiple signaling pathway outputs. In this review, we
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