推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, human
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... PIK3R1(5295)
一般描述
Anti-PI 3-Kinase antibody (06-195) covalently coupled to protein A-agarose by dimethyl-pimelimidate.
应用
Anti-PI3 Kinase Antibody, p85, agarose conjugate detects level of PI3 Kinase & has been published & validated for use in IP.
特点和优势
Format: Gel Immobilized
质量
routinely evaluated by immunoprecipitating PI 3-Kinase from RIPA lysate of EGF-stimulated human A431 carcinoma cells
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.
Rabinovsky, R; Pochanard, P; McNear, C; Brachmann, SM; Duke-Cohan, JS; Garraway, LA; Sellers, WR
Molecular and cellular biology null
Thomas A Blair et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(8), 1681-1688 (2014-06-07)
Platelet hyperactivity is a contributing factor in the pathogenesis of cardiovascular disease and can be induced by elevated levels of circulating growth factors, such as insulin-like growth factor-1 (IGF-1). IGF-1 is a primer that cannot stimulate platelet activation by itself
Timothy J Thauland et al.
Frontiers in immunology, 10, 753-753 (2019-04-30)
Gain-of-function variants in p110δ, the catalytic subunit of phosphatidylinositol 3-kinase (PI3K) expressed in lymphocytes, cause activated PI3-kinase δ syndrome (APDS), a primary immunodeficiency that is characterized by recurrent infections, viremia, lymphadenopathy, and autoimmunity. The mechanism of autoimmunity in APDS has
Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle.
McCurdy, CE; Davidson, RT; Cartee, GD
American Journal of Physiology. Endocrinology and Metabolism null
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