产品名称
LiChrospher® 100 RP-18 endcapped (5µm) LiChroCART™ 125-4.6, suitable for HPLC
material
stainless steel column
agency
suitable for USP L1
product line
LiChrospher®
feature
endcapped
packaging
1 ea of
extent of labeling
21.6% Carbon loading
parameter
250 bar pressure, 60 °C max. temp.
technique(s)
HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)
column L × I.D.
12.5 cm × 4.6 mm
surface area
350 m2/g
matrix
fully porous particle
matrix active group
C18 bonding phase
particle size
5 μm
pore size
100 Å pore size
operating pH range
2-7.5
separation technique
reversed phase
storage temp.
no temp limit
General description
HPLC cartridge
Application
- Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry: This study effectively utilizes the Ascentis® Express F5, 2.7 μm HPLC column to analyze complex pharmaceutical mixtures and identify degradation products, demonstrating the column′s high-resolution capabilities and robust performance in pharmaceutical analysis (Özcan et al., 2023).
- Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product: This research highlights the use of the Ascentis® Express F5 HPLC column in developing stability-indicating methods for the analysis of tasimelteon, underscoring its crucial role in ensuring the quality and safety of pharmaceuticals through advanced analytical techniques (Özcan et al., 2020).
Legal Information
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
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