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Merck
CN
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主要文件

安全信息

14-724

Sigma-Aldrich

CLK3 Protein, active, 10 µg

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About This Item

UNSPSC代码:
12352202
eCl@ss:
32160405

重组

expressed in baculovirus infected Sf21 cells

质量水平

描述

protein target CLK3

纯化方式

(Ni2+/NTA-agarose)

技术

activity assay: suitable

UniProt登记号

基因信息

human ... CLK3(1198)

一般描述

FUNCTION: SwissProt: P49761 # Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates serines, threonines and tyrosines.
SIZE: 638 amino acids; 73515 Da
SUBCELLULAR LOCATION: Nucleus. Cytoplasm (By similarity). Acrosome (By similarity).
PTM: Autophosphorylates on all three types of residues (By similarity).
SIMILARITY: SwissProt: P49761 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. & Contains 1 protein kinase domain.

质量

routinely evaluated by phosphorylation of 500μM PKC Substrate Peptide 2 (Catalog # 12-411)

物理属性

63kDa

储存及稳定性

6 months at -70°C from date of shipment

分析说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

法规信息

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