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Merck
CN
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文件

14-720-M

Sigma-Aldrich

FAK Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686, for use in Kinase Assays.

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About This Item

UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物来源

human

质量水平

重组

expressed in baculovirus infected Sf21 cells

产品线

Upstate®

比活

(For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)

分子量

Mw 35.5 kDa

纯化方式

(Ni2+/NTA-agarose)

种属反应性

human

制造商/商品名称

Upstate®

技术

activity assay: suitable (kinase)

登记号

 (FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. )
NM_005607.3

UniProt登记号

相关疾病

obesity; metabolic disorders

基因信息

human ... PTK2(5747)

一般描述

N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686

生化/生理作用

Protein Target: FAK

包装

Also available in 10 μg size and in bulk

质量

routinely evaluated by phosphorylation of 100μM substrate peptide (EEEEYEEEEEEYYIIEEEEEEYEEEEEEYYEEEEEEKKK)

目标描述

FAK

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°C)

Not applicable


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