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Merck
CN
所有图片(1)

文件

14-692-M

Sigma-Aldrich

DAPK1 Protein, active, 10 µg

Active, N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296, for use in Kinase Assays.

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UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物来源

human

质量水平

100
300

重组

expressed in baculovirus infected Sf21 cells

分子量

Mw 60.9 kDa

制造商/商品名称

Upstate®

技术

activity assay: suitable (kinase)

NCBI登记号

UniProt登记号

基因信息

human ... DAPK1(1612)

一般描述

N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296

生化/生理作用

Protein Target: DAPK1

质量

routinely evaluated by phosphorylation of ZIPtide (Catalog #12-545)

储存及稳定性

stable 6 months at -70°C from date of shipment

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Epigenetic change in pituitary tumorigenesis.
Farrell, W E and Clayton, R N
Endocrine-Related Cancer, 10, 323-330 (2003)
DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death.
Bialik, Shani and Kimchi, Adi
Seminars in cancer biology, 14, 283-294 (2004)
Anastasia V Velentza et al.
Pharmacology & therapeutics, 93(2-3), 217-224 (2002-08-23)
Death-associated protein kinase (DAPK) is a calmodulin-regulated serine/threonine protein kinase associated with neuronal cell death in animal models of disease. The recent determination of the 1.5A crystal structure of the catalytic kinase domain of DAPK, the discovery of amino acid
The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases.
Shohat, Galit, et al.
Biochimica et Biophysica Acta, 1600, 45-50 (2002)

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