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Merck
CN
所有图片(1)

文件

14-683-M

Sigma-Aldrich

PAK3 Protein, active, 10 µg

Active, C-terminal 6His-tagged, recombinant, human full length, PAK3. For use in Kinase Assays.

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所有图片(1)
UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物来源

human

质量水平

100
300

重组

expressed in baculovirus infected Sf21 cells

分子量

Mw 63.2 kDa

制造商/商品名称

Upstate®

技术

activity assay: suitable (kinase)

NCBI登记号

NM_002578.2

UniProt登记号

O75914

基因信息

human ... PAK3(5063)

一般描述

C-terminal 6His-tagged, recombinant, human full length, PAK3.

mitosis
Product Source: PAK3 expressed by baculovirus in Sf21 cells.

应用

Research Category
Inflammation & Immunology

生化/生理作用

Protein Target: PAK3
Target Sub-Family: STE

质量

routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).

外形

Ni2+/NTA-agarose

储存及稳定性

6 months at -70°C from date of shipment

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317

危险分类

Skin Sens. 1

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Rho proteins, mental retardation and the neurobiological basis of intelligence.
van Galen, Elly J M and Ramakers, Ger J A
Progress in Brain Research, 147, 295-317 (2005)
Ger J A Ramakers
Trends in neurosciences, 25(4), 191-199 (2002-05-10)
For several decades, it has been known that mental retardation (MR) is associated with abnormalities in dendrites and dendritic spines. The recent cloning of seven genes that cause nonspecific MR when mutated provides important insights in the cellular mechanisms that
J Roig et al.
Vitamins and hormones, 62, 167-198 (2001-05-11)
The p21-activated protein kinase gamma-PAK, also known as PAK2, has very different properties from the other two highly conserved isoforms of the PAK family, alpha-PAK (PAK1) and beta-PAK (PAK3). gamma-PAK has cytostatic activity, as shown by inhibition of cleavage of
Zahara M Jaffer et al.
The international journal of biochemistry & cell biology, 34(7), 713-717 (2002-04-16)
The p21-activated kinases (Paks) are serine/threonine protein kinases that bind to and, in some cases, are stimulated by activated forms of the small GTPases, Cdc42 and Rac. With the recent discovery of several novel isoforms, Paks are now categorized into

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