生物来源
human
质量水平
100
300
重组
expressed in baculovirus infected Sf21 cells
分子量
Mw 49.6 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
NCBI登记号
UniProt登记号
基因信息
human ... HIPK2(28996)
一般描述
N-terminal His6-tagged, recombinant, human HIPK2, amino acids 165-564
Product Source: baculovirus in Sf21 insect cells
应用
Research Category
Inflammation & Immunology
Inflammation & Immunology
生化/生理作用
Protein Target: HIPK2
Target Sub-Family: CMGC
质量
routinely evaluated by phosphorylation of 0.33mg/ml MBP (Catalog # 13-104)
外形
Ni2+/NTA-agarose
储存及稳定性
6 months at -70°C
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Jae J Song et al.
The Journal of biological chemistry, 278(47), 47245-47252 (2003-09-12)
Overexpression of JNK binding domain inhibited glucose deprivation-induced JNK1 activation, relocalization of Daxx from the nucleus to the cytoplasm, and apoptosis signal-regulating kinase 1 (ASK1) oligomerization in human prostate adenocarcinoma DU-145 cells. However, SB203580, a p38 inhibitor, did not prevent
Jeffrey A Ecsedy et al.
Molecular and cellular biology, 23(3), 950-960 (2003-01-17)
We describe an interaction between homeodomain-interacting protein kinase 1 (HIPK1) and Daxx, two transcriptional regulators important in transducing growth-regulatory signals. We demonstrate that HIPK1 is ubiquitously expressed in mice and humans and localizes predominantly to the nucleus. Daxx normally resides
Y H Kim et al.
The Journal of biological chemistry, 273(40), 25875-25879 (1998-09-25)
A novel family of cofactors that differentially interact with homeoproteins have been identified via a yeast two-hybrid screen. The proteins contain a conserved protein kinase domain that is separated from a domain that interacts with homeoproteins and hence are termed
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