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Merck
CN
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主要文件

14-607-M

Sigma-Aldrich

PIM2 Protein, active, 25 µg

Active, human PIM2 expressed in E. coli, purified using GSH agarose, for use in Kinase Assays.

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About This Item

UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物来源

human

质量水平

分子量

Mw 63.4 kDa

制造商/商品名称

Upstate®

技术

activity assay: suitable (kinase)

NCBI登记号

UniProt登记号

基因信息

human ... PIM2(11040)

一般描述

Product Source: N-terminal GST-tagged recombinant full-length human PIM2
human PIM2 expressed in E. coli, purified using GSH agarose

质量

routinely evaluated by phosphorylation of PIM2tide

外形

GSH agarose

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Casey J Fox et al.
Genes & development, 17(15), 1841-1854 (2003-07-19)
Growth factor withdrawal results in the termination of factor-dependent transcription. One transcript that declines rapidly following growth factor deprivation of hematopoietic cells is the serine/threonine kinase pim-2. When constitutively expressed, Pim-2 conferred long-term resistance to a variety of apoptotic stimuli
Bin Yan et al.
The Journal of biological chemistry, 278(46), 45358-45367 (2003-09-05)
Hematopoietic growth factors mediate the survival and proliferation of blood-forming cells, but the mechanisms through which these proteins produce their effects are incompletely known. Recent studies have identified the pim family of kinases as mediators of cytokine-dependent survival signals. Several

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