Arg Protein, active, human, 10 µg

FUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
COFACTOR: Magnesium or manganese.
SIZE: 1182 amino acids; 128343 Da
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Widely expressed.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.

Routinely evaluated by phosphorylation of Abltide.

121.9 kDa

6 months at -70°C

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

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