产品名称
Cdk5/p35蛋白,活性,10 µg, Active complex of recombinant full length human Cdk5 containing & N-terminal His6-tag & recombinant full-length human p35 containing an N-terminal GST-tag, for use in Kinase Assays.
biological source
human
recombinant
expressed in baculovirus infected Sf21 cells
mol wt
Mw 34 kDa (cdk5)
Mw 61 kDa (p35 with GST-tag)
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Quality Level
Analysis Note
通过组蛋白H1的磷酸化进行常规评估
Biochem/physiol Actions
蛋白质靶标:CDK5/p35
靶标亚家族:CMGC
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
产品来源:两者均由杆状病毒在Sf21昆虫细胞中表达
含有N-末端His6标签重组全长人Cdk5以及含有N-末端GST标签的重组全长人p35的复合物
Other Notes
比活相关数据,请参阅检验报告以获取该酶的单独批次。
Packaging
也提供250μg规格(目录号14-477M)-请查询价格和供货情况。
Physical form
Ni-NTA琼脂糖
Preparation Note
在-70°C下保存1年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Ward G Walkup et al.
eLife, 5 (2016-10-21)
SynGAP is a Ras/Rap GTPase-activating protein (GAP) that is a major constituent of postsynaptic densities (PSDs) from mammalian forebrain. Its α1 isoform binds to all three PDZ (PSD-95, Discs-large, ZO-1) domains of PSD-95, the principal PSD scaffold, and can occupy
Ward G Walkup et al.
The Journal of biological chemistry, 290(8), 4908-4927 (2014-12-24)
synGAP is a neuron-specific Ras and Rap GTPase-activating protein (GAP) found in high concentrations in the postsynaptic density (PSD) fraction from the mammalian forebrain. We have previously shown that, in situ in the PSD fraction or in recombinant form in
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