biological source
human
mol wt
Mw 105 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase), western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... FOXO1(2308)
General description
Product Source: Recombinant human expressed in E. coli
Application
N-terminal, Glutathione-Stransferase (GST) tagged, full-length fusion protein corresponding to human FKHR.
Physical form
Glutathione-agarose
Preparation Note
1 year at -70°C
Analysis Note
routinely evaluated by phosphorylation by Akt1
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Arthur Bikbaev et al.
Scientific reports, 5, 14527-14527 (2015-09-30)
The formation and maintenance of connectivity are critically important for the processing and storage of information in neuronal networks. The brain extracellular matrix (ECM) appears during postnatal development and surrounds most neurons in the adult mammalian brain. Importantly, the removal
Stefan Weigel et al.
Journal of neurophysiology, 107(2), 640-648 (2011-10-28)
The midbrain is an important processing area for sensory information in vertebrates. The optic tectum and its mammalian counterpart, the superior colliculus, receive multimodal, topographic information and contain a sensory map that plays a role in spatial attention and orientation
Andrew J Weitz et al.
Neuron, 104(6), 1153-1167 (2019-11-02)
Anatomical and behavioral data suggest that the ventrolateral orbitofrontal cortex (VLO), which exhibits extensive connectivity and supports diverse sensory and cognitive processes, may exert global influence over brain activity. However, this hypothesis has never been tested directly. We applied optogenetic
Hidetoshi Amita et al.
Science advances, 5(8), eaaw9297-eaaw9297 (2019-08-29)
The essential everyday task of making appropriate choices is a process controlled mainly by the basal ganglia. To this end, subjects need not only to find "good" objects in their environment but also to reject "bad" objects. To reveal this
Rashmi N Kumar et al.
Molecular and cellular biology, 26(1), 50-62 (2005-12-16)
The GTPase-deficient, activated mutant of Galpha12 (Galpha12Q229L, or Galpha12QL) induces neoplastic growth and oncogenic transformation of NIH 3T3 cells. Using microarray analysis, we have previously identified a role for platelet-derived growth factor receptor alpha (PDGFRalpha) in Galpha12-mediated cell growth (R.
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