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Merck
CN
所有图片(1)

文件

14-253-M

Sigma-Aldrich

p38β2/SAPK2b2 Protein, active, 10 µg

Active, N-terminal GST fusion protein corresponding to full length human p38β2/SAPK2b2 activated with MKK6. For use in Kinase Assays.

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UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物来源

human

质量水平

分子量

Mw 71 kDa

制造商/商品名称

Upstate®

技术

activity assay: suitable (kinase)

NCBI登记号

UniProt登记号

一般描述

N-terminal GST fusion protein corresponding to full length human p38β2/SAPK2b2 activated with MKK6.
Product Source: full length human p38β2/SAPK2b2, expressed in E. coli.

生化/生理作用

Protein Target: p38β2/SAPK2b2
Target Sub-Family: CMGC

质量

routinely evaluated by phosphorylation of myelin basic protein

外形

Affinity chromatography on glutathione-agarose beads

储存及稳定性

6 months at -20°C

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

WGK

WGK 2


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A Cuenda et al.
The EMBO journal, 16(2), 295-305 (1997-01-15)
Stress-activated protein kinase-3 (SAPK3), a recently described MAP kinase family member with a wide-spread tissue distribution, was transfected into several mammalian cell lines and shown to be activated in response to cellular stresses, interleukin-1 (IL-1) and tumour necrosis factor (TNF)
A Cuenda et al.
FEBS letters, 364(2), 229-233 (1995-05-08)
A class of pyridinyl imidazoles inhibit the MAP kinase homologue, termed here reactivating kinase (RK) [Lee et al. (1994) Nature 372, 739-746]. We now show that one of these compounds (SB 203580) inhibits RK in vitro (IC50 = 0.6 microM)

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