生物来源
mouse
质量水平
重组
expressed in E. coli
分子量
Mw 67.8 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
NCBI登记号
UniProt登记号
运输
dry ice
一般描述
Product Source: expressed in E coli
Recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused with GST at the N terminus
质量
routinely evaluated by phosphorylation of MBP (Catalog # 13-104) substrate in vitro.
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 2
Tian-Rui Xu et al.
The Biochemical journal, 413(1), 51-60 (2008-04-26)
FRET (fluorescence resonance energy transfer) and co-immunoprecipitation studies confirmed the capacity of beta-arrestin 2 to self-associate. Amino acids potentially involved in direct protein-protein interaction were identified via combinations of spot-immobilized peptide arrays and mapping of surface exposure. Among potential key
D Aronson et al.
The Journal of biological chemistry, 272(41), 25636-25640 (1997-11-05)
Contractile activity plays a critical role in the regulation of gene transcription in skeletal muscle, which in turn determines muscle functional capabilities. However, little is known about the molecular signaling mechanisms that convert contractile activity into gene regulatory responses in
Maofu Fu et al.
Methods in molecular biology (Clifton, N.J.), 284, 15-36 (2004-06-03)
Signal transduction pathways mediate cell-cell interactions and integrate signals from the extracellular environment through specific receptors at the cell membrane. They play a pivotal role in regulating cellular growth and differentiation and in mediating many physiological and pathological processes, such
Okano J et al.
The Journal of biological chemistry, 276(22), 19555-19564 (2001-03-30)
Paclitaxel is a widely used chemotherapeutic agent and is known to induce programmed cell death (apoptosis) in a variety of cell types, but the precise underlying mechanisms are poorly understood. To elucidate these mechanisms, we challenged human esophageal squamous cancer
O Zugasti et al.
Molecular and cellular biology, 21(19), 6706-6717 (2001-09-05)
Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in primary mouse fibroblasts and are potent inducers of
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