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方案
≥95% (SDS-PAGE)
表单
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
溶解性
water: 20 mg/mL
储存温度
2-8°C
SMILES字符串
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
一般描述
人血清白蛋白(HSA)是可溶性的非糖基化球状蛋白单体，是血浆中含量最为丰富的蛋白。由I、II和III三个同源结构域组成多个结构域的蛋白质。每个结构域包含子域A和B，具有相同的结构基元。HSA基因位于人类染色体4q13.3上。
生化/生理作用
人血清白蛋白(HSA)是脂肪酸、甲状腺激素和类固醇的主要载体蛋白。对细胞外液量的稳定起关键作用。HSA可用作疫苗和治疗性蛋白质药物的赋形剂。还可用作疫苗和药物生产中的细胞培养基补充剂。HSA用于治疗血液透析、急性肝功能衰竭、慢性肝病等。HSA适用于各种生物应用，包括配体捕获、纳米给药和融合蛋白等。
警告
毒性：标准处理（A）
重悬
复溶后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多6个月。
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Yang He et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(47), 19078-19083 (2011-11-02)
Human serum albumin (HSA) is widely used in clinical and cell culture applications. Conventional production of HSA from human blood is limited by the availability of blood donation and the high risk of viral transmission from donors. Here, we report
Angelica M Merlot et al.
Frontiers in physiology, 5, 299-299 (2014-08-28)
Serum albumin is a multi-functional protein that is able to bind and transport numerous endogenous and exogenous compounds. The development of albumin drug carriers is gaining increasing importance in the targeted delivery of cancer therapy, particularly as a result of
Gabriella Fanali et al.
Molecular aspects of medicine, 33(3), 209-290 (2012-01-11)
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an extraordinary ligand binding capacity
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