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ligand
(Carboxyethyl with Alkyl-Functional Groups)
物料
polypropylene housing
无菌性
non-sterile (
sterile)
产品线
Eshmuno®
形式
prepacked column
参数
≤8 bar pressure
300 cm/hr max. flow rate
体积
0.6 mL
基质活性基团
Polyvinyl Ether
平均粒径
50 μm
容量
~60 mL, resin binding capacity
应用
ADC
mAb
recombinant protein
储存温度
15-25°C
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一般描述
Eshmuno® CMX chromatography resin is a mixed mode chromatography resin built on the proven Eshmuno® resin technology. This innovative resin combines weak cation exchange properties with hydrophobic interaction, providing high selectivity for Monoclonal Antibody (mAb), fusion protein and Antibody Drug Conjugate (ADCs) purification as well as separation of low molecular weight impurities, Host Cell Proteins (HCPs) and glycovariants.
应用
Purification of mAbs, ADCs, fusion proteins
特点和优势
Eshmuno® CMX chromatography resin enables users to
- Intensify processes and decrease costs by reducing the number of chromatographic steps and buffer consumption
- Improve performance with higher recovery rates, high selectivity and superior dynamic binding capacity
- Improve the user experience with a broad operational window, simplified process development and easy column packing due to a rigid base bead
法律信息
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
法规信息
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