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Merck
CN
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文件

12-242

Sigma-Aldrich

Glycogen Synthase Peptide-2

Ala21, negative control for GSK-3β

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UNSPSC代码:
12352204
eCl@ss:
32160405
NACRES:
NA.42

product name

Glycogen Synthase Peptide-2 (Ala21), Glycogen Synthase Peptide-2 (Ala21) primarily used in Kinase Assays.

质量水平

制造商/商品名称

Upstate®

技术

activity assay: suitable (kinase)

UniProt登记号

运输

wet ice

质量

Routinely evaluated for use as a negative control for assay of GSK-3β (Catalog # 14-306) activity in a phosphorylation assay. Not to be used as a substrate for GSK3.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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M P Coghlan et al.
Chemistry & biology, 7(10), 793-803 (2000-10-18)
Glycogen synthase kinase-3 (GSK-3) is a serine/threonine protein kinase, the activity of which is inhibited by a variety of extracellular stimuli including insulin, growth factors, cell specification factors and cell adhesion. Consequently, inhibition of GSK-3 activity has been proposed to
Regulation and functions of the glycogen synthase kinase-3 subfamily.
Woodgett, J R
Seminars in cancer biology, 5, 269-275 (1994)
S R Kimball et al.
The Journal of biological chemistry, 273(47), 30945-30953 (1998-11-13)
The present study was designed to investigate the mechanism through which leucine and histidine regulate translation initiation in L6 myoblasts. The results show that both amino acids stimulate initiation and coordinately regulate the activity of eukaryotic initiation factor eIF2B. The

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