Eshmuno^® S

The first member of the Eshmuno^® resin family, designed specifically for highly productive downstream bioprocessing

Eshmuno^® S chromatography resin enables:

• Purification of basic and neutral proteins (e.g., antibodies) and peptides specifically designed for highly productive downstream bioprocessing
• High flow rate applications
• High separation efficiency over a broad range of flow rates with a rigid matrix and optimized pore structure
• Tentacle technology which provides high yield, selectivity, and focused elution
• Multiple CIP and packing cycles with the chemically and physically robust bead, leading to a longer resin lifetime
• Compatibility with 1 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl and storage solutions 0.1 M NaOH

Plastic bottle

Appearance: Milky cream coloured turbid suspension, free from coarse mechanical impurities.
Microscopic evaluation: Spherical particles, no agglomerates, no fines.
Extractable matter (water): ≤ 0.08 %
Ionic capacity: 50 - 100 µeq/ml
Performance test (chymotrypsinogen): 10 - 30 mS/cm
Performance test (lysozyme): 35 - 55 mS/cm
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Protein binding capacity (lysozyme): 120 - 180 mg/ml
Particle size (50-120 µm): ≥ 80 %
Particle size (d50): 75 - 95 µm
Cerium: ≤ 30 µg/g
Endotoxins: ≤ 1.00 EU/ml
TAMC (total aerobic microbial count): ≤ 100 CFU/ml
TYMC (total yeast and mould count): ≤ 100 CFU/ml

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany