跳转至内容

尊敬的客户:

目前国际形势复杂多变,关税政策尚不明朗,这可能对我们的产品价格产生一定影响。在此情况下,我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性,如果您选择在此期间下单,我们将保留根据实际情况调整价格的权利。同时,我们也理解市场变化可能给您带来的困扰,因此如果在订单实际发货前因关税政策变动导致价格出现较大波动,默克将与您进行协商讨论并视情况对订单进行调整或取消。

Merck
CN
所有图片(2)

主要文件

1.16884

Millipore

Fractogel EMD DMAE (M)

别名:

Fractogel® EMD DMAE (M)

登录查看公司和协议定价

选择尺寸

10 ML
¥833.94
100 ML
¥4,186.65

¥833.94


预计发货时间2025年4月21日详情



选择尺寸

变更视图
10 ML
¥833.94
100 ML
¥4,186.65

About This Item

UNSPSC代码:
41115711

¥833.94


预计发货时间2025年4月21日详情


质量水平

ligand

diethylaminoethyl

描述

weak anion exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)

无菌性

sterile (Caustic Stable)

产品线

Fractogel®

表单

resin

参数

170 cm/hr flow rate
8 bar max. pressure

基质活性基团

methacrylate

平均粒径

40-90 μm

容量

100 mg binding capacity (BSA/mg of resin)

正在寻找类似产品? 访问 产品对比指南

一般描述

Weak anion exchange Fractogel® resin featuring the tentacle technology, for purification of acidic and neutral proteins and peptides from multiple sources, pDNA purification, DNA, RNA, and endotoxin removal, large viruses purification, vaccine purification, blood fractionation, and more

特点和优势

Fractogel® EMD DMAE (M) enables:
  • Excellent binding to large viruses and plasmid DNA
  • Homogenous binding with high selectivity and purity
  • Lower elution volumes for the highest purity levels
  • Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution


Due to the titration behavior, the ion exchange capacity can be used from pH 2 to pH 9.5. The separation of proteins is based on reversible electrostatic interactions between the negatively charged regions of the proteins′ surface and the support. Proteins are retained efficiently on Fractogel® EMD DEAE when the pH of the buffer is about 1 unit above their isoelectric points (pl).

The strength of the binding depends on the following:
  • the buffer system
  • pH value of the buffer which determines the surface charge of the protein
  • the degree of the ionization of the functional groups of the exchanger
  • the concentration of the counter ions
  • the charge density on the support (protein binding capacity)

包装

  • 1.16884.0100: Fractogel® EMD DMAE (M) Resin 100ml
  • 1.16884.0010: Fractogel® EMD DMAE (M) Resin 10ml
  • 1.16884.0500: Fractogel® EMD DMAE (M) Resin 500ml
  • 1.16884.5000: Fractogel® EMD DMAE (M) Resin 5L

Plastic bottle

分析说明

Appearance: Milky, turbid suspension,free from impurities (foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates, no fines
Extractable matter (water): ≤ 0.03 %
Cerium: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (bovine serum albumin): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.25
Functional test: Separation of conalbumin and human serum albumin

法律信息

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Flame

警示用语:

Warning

危险声明

危险分类

Flam. Liq. 3

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

95.0 °F

闪点(°C)

35 °C

  • 技术规格说明书

  • 什么是Emprove®程序?

    Emprove® 程序是提供我们过滤器、一次性组件、制药原料和初始材料的全面而详尽文档的系统。

    Material Qualification Dossier

    免费 - 注册下载

    Operational Excellence Dossier

    可通过订阅或付费获得

    了解更多权益。 Emprove® 程序订阅所提供的好处
    为何这些文件不可用?
    Emprove®档案所包含的信息旨在为药品生产商的注册和风险评估活动提供支持,其中有一些机密信息。如果您想访问这些信息,请联系我们

    已有该产品?

    在文件库中查找您最近购买产品的文档。

    访问文档库

    商品

    See case study examples of how to optimize chromatographic purification of plasmid DNA for Biopharmaceutical Applications.

    Influenza vaccines are commonly made using egg-based and cell-based manufacturing strategies. Find step-by-step information on the manufacturing process for each method.

    A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understanding, simulates bottlenecks, and helps to optimize production efficiency.

    Learn more one the attenuated viral vaccines manufacturing process: cell culture, clarification, nuclease treatment, chromatography, and sterile filtration.

    查看所有结果

    相关内容

    通过合作进行量身定制的病毒疫苗生产,应对病毒特有的挑战。

    This technical article breaks down the adenovirus vaccine manufacturing process and provides a case study on developing an accelerated and cost-effective single-use adenoviral vector vaccine.

    我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持