产品名称
醛脱氢酶, lyophilized, from yeast, pkg of 100 units/vial
biological source
yeast
form
lyophilized
specific activity
≥15 U/mg (calculated on the protein content)
packaging
pkg of 100 units/vial
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
醛脱氢酶（ALDH）代谢内源和外源的活性化合物，以维持细胞稳态。这组酶催化醛的NADP+-依赖性不可逆氧化形成羧酸。.ALDH 同工酶具有广泛的底物特异性。由于底物积累，ALDH的失活导致细胞毒性。
General description
醛脱氢酶（ALDH）形成一期氧化酶亚家族，在真细菌、真核细胞、古生菌和其它活微生物中显示出进化保守性。ALDH 在肝中大量表达，并存在于肝组织。它们位于细胞质、线粒体、内质网和细胞核。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Kim Shortall et al.
Frontiers in molecular biosciences, 8, 659550-659550 (2021-06-01)
Aldehyde dehydrogenases engage in many cellular functions, however their dysfunction resulting in accumulation of their substrates can be cytotoxic. ALDHs are responsible for the NAD(P)-dependent oxidation of aldehydes to carboxylic acids, participating in detoxification, biosynthesis, antioxidant and regulatory functions. Severe
Endogenous Mitochondrial Aldehyde Dehydrogenase-2 as an Antioxidan
Patel VB, et al.
Liver, 247-259 (2018)
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