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Merck
CN
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文件

安全信息

1.08262

Supelco

三氟乙酸

for spectroscopy Uvasol®

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别名:
TFA
线性分子式:
CF3COOH
CAS号:
分子量:
114.02
Beilstein:
742035
MDL编号:
UNSPSC代码:
12191502
EC索引号:
200-929-3
NACRES:
NA.03

蒸汽密度

3.9 (vs air)

质量水平

蒸汽压

97.5 mmHg ( 20 °C)

检测方案

≥99.8% (acidimetric)

形式

liquid

技术

UV/Vis spectroscopy: suitable

杂质

≤10% Water (Karl Fischer)

蒸发残留物

≤0.005%

颜色

APHA: ≤10

透射比

265 nm, ≥10.0%
305 nm, ≥50.0%
320 nm, ≥80.0%
325 nm, ≥90.0%

折射率

n20/D 1.3 (lit.)

pH值(酸碱度)

1 (10 g/L in H2O)

bp

72.4 °C (lit.)

mp

−15.4 °C (lit.)

溶解性

soluble 10 g/mL

密度

1.489 g/mL at 20 °C (lit.)

储存温度

2-30°C

SMILES字符串

OC(C(F)(F)F)=O

InChI

1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

DTQVDTLACAAQTR-UHFFFAOYSA-N

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一般描述

UV/VIS 和红外光谱中分析结果的准确性取决于是否使用非常纯的溶剂进行样品制备。Uvasol<TMSYMBOL></TMSYMBOL> 系列是特别被计为用于光谱学和其它需要最高光学纯度化学物质的应用领域。精制过程使得应用更加安全并避免由痕量 UV(紫外线)、IR(红外线)和荧光污染引起对分析结果的错误判断。Uvasol<TMSYMBOL></TMSYMBOL> 溶剂可提供最佳的紫外线透射率。在所有规范中,均确定了 5 种典型波长的最小透射率。

应用


  • Characterization of ribostamycin and its impurities using a nano-quantity analyte detector: This study examines ribostamycin and its impurities using a nano-quantity analyte detector and details a systematic comparison of three different aerosol detectors. The role of trifluoroacetic acid as a mobile phase additive enhances detection sensitivity and analytical precision, making it crucial for accurate impurity profiling and pharmaceutical quality control (Meng et al., 2024).

  • Paradigm Shift: Major Role of Ion-Pairing-Dependent Size Exclusion Effects in Bottom-Up Proteomics Reversed-Phase Peptide Separations: This research highlights the critical role of trifluoroacetic acid in modifying the ion-pairing and size exclusion properties of peptides during reversed-phase separations in proteomics. The study provides a deeper understanding of the mechanisms influencing peptide behavior, which is essential for developing more effective analytical techniques (Yeung et al., 2024).

  • New fabric phase sorptive extraction for nondestructive analysis of heritage textile samples: This paper introduces a novel fabric phase sorptive extraction method using trifluoroacetic acid among other solvents to analyze heritage textile samples nondestructively. This method demonstrates significant potential in cultural heritage preservation and forensic science by allowing detailed analysis without damaging the original artifacts (Tanasescu et al., 2024).

  • Preparation and characterization of stationary phase gradients on C8 liquid chromatography columns: The study discusses the preparation and characterization of stationary phase gradients for chromatography columns, with trifluoroacetic acid used to adjust the pH and ionic strength of the mobile phase. This modification is shown to enhance the chromatographic separation of complex mixtures, proving vital for analytical and preparative scale separations (Cecil et al., 2024).

  • Optimization of Cyanocobalamin (Vitamin B(12)) Sorption onto Mesoporous Superparamagnetic Iron Oxide Nanoparticles: This investigation utilizes trifluoroacetic acid in the synthesis and functionalization of nanoparticles for efficient vitamin B(12) sorption. The study explores the implications for targeted drug delivery systems and bioseparation, demonstrating the adaptability and effectiveness of these engineered nanoparticles (Flieger et al., 2024).

分析说明

含量(酸度): ≥ 99.8 %
水(K.F.): ≤ 0.10 %
色号(Apha): ≤ 10
蒸发残留物: ≤ 0.005 %
透射率(265 nm处): ≥ 10.0 %
透射率(305 nm处): ≥ 50.0 %
透射率(320 nm处): ≥ 80.0 %
透射率(从325起 nm开始): ≥ 90.0 %

其他说明

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

法律信息

UVASOL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 2

闪点(°F)

212.0 °F - Pensky-Martens closed cup

闪点(°C)

> 100 °C - Pensky-Martens closed cup

法规信息

危险化学品

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实验方案

Straightforward HPTLC-MS analysis of lactose in dairy products (milk or yoghurt) using only protein crash, centrifugation and dilution as sample preparation.

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Catalyst screening kits, KitAlysis™, and TLC-MS analysis enable high-throughput synthesis and analysis for efficient reactions.

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